Clinical Factors Influencing Improvement in Disorganization in Clinical High‐Risk for Psychosis: Preliminary Findings From a 2‐Year Follow‐Up

Asia-Pacific Psychiatry 2026 Open access

Read full text
Authors: Lorenzo Pelizza, Emanuela Leuci, Emanuela Quattrone, Michele Occhionero, Arianna Biancalani, Derna Palmisano, Simona Pupo, Giuseppina Paulillo, Clara Pellegrini, Pietro Pellegrini, Marco Menchetti
DOI: 10.1111/appy.70021
Cited by: 1
References: 6

Abstract

Disorganization is under-treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR-P) across 2 years of follow-up. About 180 participants completed the GAF and the PANSS. Longitudinally, 111 (61.7%) individuals had a decrease in disorganization. Significant associations of this improvement were with shorter duration of untreated illness, higher improvement in negative symptoms, and antipsychotic prescription.

Fields of Study & Subjects

Schizophrenia research and treatment Personality Disorders and Psychopathology Psychotherapy Techniques and Applications

Publication details

Journal / source
Asia-Pacific Psychiatry
Publisher
Wiley
Volume
18
Issue
2
Pages
e70021–e70021
Publication date
8 April 2026
Language
EN