Prospective implementation of the HCT frailty scale in adults with lymphoproliferative syndromes candidates for autologous haematopoietic stem cell transplantation: Results from a multicentre GETH‐TC study

British Journal of Haematology 2026 Open access

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Authors: Javier Cornago, Mónica Baile, Marina Acera, Laura Fox, María del Mar Pérez-Artigas, Ana Santamaria, María Del Carmen Quintela, Andrés Sánchez-Salinas, Joaquina M Salmerón, Verónica Illana, Zahra Abdallahi‐Lefdil, Laura Pardo
+19 more Laura Solán, José Luis López-Lorenzo, Sara Fernández‐Luis, Leddy Patricia Vega, Sara Villar, Patricia Beorlegui‐Murillo, Mònica Molina, Albert Esquirol, Isabel Izquierdo, Julia Ribes, Alberto Mussetti, Esperanza Lavilla, Olga Alda, Javier López-Marín, Leyre Bento, Silvia Filaferro, Pascual Balsalobre, A. Sureda, María Queralt Salas
DOI: 10.1111/bjh.70505
Cited by: 1
References: 38

Abstract

This prospective study evaluated the incidence and dynamics of frailty in 156 adults with lymphoproliferative syndromes undergoing autologous haematopoietic stem cell transplantation (HSCT). Frailty was assessed using the haematopoietic cell transplantation (HCT) frailty scale in patients from 15 Spanish institutions at initial consultation, transplant admission and day +100. Quality of life (QoL) was measured using the EuroQoL. At first consultation, 45 patients (28.8%) were classified as fit, 93 (59.6%) as pre-frail and 18 (11.6%) as frail. Frailty was more frequent among older patients, those with Karnofsky performance status (KPS) below 90%, and abnormal Mini-Cog scores (

Fields of Study & Subjects

Frailty in Older Adults Childhood Cancer Survivors' Quality of Life Hematopoietic Stem Cell Transplantation

Publication details

Journal / source
British Journal of Haematology
Publisher
Wiley
Volume
209
Issue
1
Pages
197–209
Publication date
29 April 2026
Language
EN