Reply to comments on cIMPACT ‐ NOW update 11

The associated commentary acknowledges that cIMPACT-NOW update 11 addresses areas of significant diagnostic uncertainty and that it provides important interim guidance for CNS tumor classification. The commentary also provides a set of comments and suggestions. In this context, it is important to understand that cIMPACT-NOW update 11 (like all cIMPACT-NOW updates) presents consensus recommendations from multiple experts in the field, with the opinions often following lengthy discussions and the weighing of different possibilities. These debates included whether other recommendations should be provided on particular topics; however, for the paper, the consensus opinions were part of cIMPACT-NOW update 11, but topics that did not yield consensus decisions were not included. Some of these latter, open-ended issues were brought up in the associated commentary. We trust that deliberations for the 6th edition of the WHO Classification of CNS Tumors, which begin in late 2025, will discuss some of these topics again, and the associated commentary provides another set of comments to inform such discussions. Data sharing not applicable to this article as no datasets were generated or analysed during the current study.