Insights Into Hereditary Alpha‐Tryptasemia From a Genome‐Wide Association Study in Hymenoptera Venom Anaphylaxis

Clinical & Experimental Allergy 2026 Open access

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Authors: Teresa Blanco‐Ramos, Raquel Cruz, Irene Fernández‐Franco, Mª Ángeles Vargas, Ángel Carracedo, Arturo González‐Quintela, C. Vidal
DOI: 10.1111/cea.70211
Cited by: 1
References: 9

Abstract

Summary The G allele in rs111911698 is strongly associated with BST ≥ 8 ng/mL and could serve as a genetic proxy for the detection of HαT in patients with Hymenoptera venom anaphylaxis. The G allele in rs111911698 is a highly sensitive and specific identifier of HαT, with high positive and negative likelihood ratios.

Fields of Study & Subjects

Food Allergy and Anaphylaxis Research Ion channel regulation and function Mast cells and histamine

Publication details

Journal / source
Clinical & Experimental Allergy
Publisher
Wiley
Volume
56
Issue
4
Pages
455–458
Publication date
7 January 2026
Language
EN