Variants in Genes Encoding Innate Lymphoid Cells Type 2 Surface Markers Affecting Asthma and Atopy Pathologies

Clinical & Experimental Allergy 2026 Open access

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Authors: Raphael Chagas Silva, Gabriela Pimentel Pinheiro, Hátilla dos Santos Silva, Talita dos Santos de Jesus, Carolina Melo Orrico-Ferreira, Jamille Souza Fernandes, Cínthia Vila Nova Santana, Carina S. Pinheiro, Ricardo Riccio Oliveira, Álvaro Augusto Cruz, Kathleen C. Barnes, Neuza Maria Alcântara Neves
+2 more Ryan dos Santos Costa, Camila Alexandrina Figueiredo
DOI: 10.1111/cea.70249
Cited by: 0
References: 6

Abstract

Summary Genetic polymorphisms on ILC2 receptors (CD127, IL‐17RB and CRTH2) increase the asthma and atopy susceptibilities. Cohort analysis suggests that alleles' combination from ILC2 variants contributes to asthma and atopy risk.

Fields of Study & Subjects

Asthma and respiratory diseases IL-33 ST2 and ILC Pathways Dermatology and Skin Diseases

Publication details

Journal / source
Clinical & Experimental Allergy
Volume
56
Issue
6
Pages
681–683
Publication date
22 February 2026
Language
EN