Acute kidney injury in hospitalised patients with type 2 diabetes: Associations with continuous glucose monitoring‐based glucose levels, mortality, and ICU admission
Abstract
AIMS: Acute kidney injury (AKI) may increase the risk of hypoglycaemia in patients with diabetes due to reduced insulin clearance and altered glucose metabolism. However, the impact of AKI on glycaemic status in non-critically ill hospitalised patients with diabetes is not well understood. METHODS: We included 166 hospitalised patients with type 2 diabetes on basal-bolus insulin monitored by continuous glucose monitoring (CGM). Kidney function was measured daily via plasma creatinine levels, and AKI was staged per Kidney Disease Improving Global Outcomes (KDIGO) guidelines. Multivariate models assessed associations between kidney function and CGM-based glycaemic outcomes. RESULTS: AKI correlated with a 7.3%-point (95% CI 0.3-14.2) reduction in time in range (TIR, 3.9-10.0 mmol/L), driven by increased time above range (TAR, >10.0 mmol/L), with no significant change in time below range (TBR,
Fields of Study & Subjects
Hyperglycemia and glycemic control in critically ill and hospitalized patients
Acute Kidney Injury Research
Potassium and Related Disorders
Publication details
- Journal / source
- Diabetic Medicine
- Publisher
- Wiley
- Volume
- 43
- Issue
- 6
- Pages
- e70321–e70321
- Publication date
- 10 April 2026
- Language
- EN