Acute kidney injury in hospitalised patients with type 2 diabetes: Associations with continuous glucose monitoring‐based glucose levels, mortality, and ICU admission

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Authors: Mikkel Thor Olsen, Kirsten Nørgaard, Signe H. Jensen, L. H. Rasmussen, Carina Kirstine Klarskov, Birgitte Lindegaard, Jonas Askø Andersen, Hans Gottlieb, Suzanne Lunding, Ulrik Pedersen‐Bjergaard, Katrine Bagge Hansen, Peter L. Kristensen
+1 more Julie M. B. Brøsen
Cited by: 1
References: 32

Abstract

AIMS: Acute kidney injury (AKI) may increase the risk of hypoglycaemia in patients with diabetes due to reduced insulin clearance and altered glucose metabolism. However, the impact of AKI on glycaemic status in non-critically ill hospitalised patients with diabetes is not well understood. METHODS: We included 166 hospitalised patients with type 2 diabetes on basal-bolus insulin monitored by continuous glucose monitoring (CGM). Kidney function was measured daily via plasma creatinine levels, and AKI was staged per Kidney Disease Improving Global Outcomes (KDIGO) guidelines. Multivariate models assessed associations between kidney function and CGM-based glycaemic outcomes. RESULTS: AKI correlated with a 7.3%-point (95% CI 0.3-14.2) reduction in time in range (TIR, 3.9-10.0 mmol/L), driven by increased time above range (TAR, >10.0 mmol/L), with no significant change in time below range (TBR,

Fields of Study & Subjects

Hyperglycemia and glycemic control in critically ill and hospitalized patients Acute Kidney Injury Research Potassium and Related Disorders

Publication details

Journal / source
Diabetic Medicine
Publisher
Wiley
Volume
43
Issue
6
Pages
e70321–e70321
Publication date
10 April 2026
Language
EN