Long‐term immune reconstitution patterns and influencing factors in people living with HIV exhibiting suboptimal immune response after 24 months of antiretroviral therapy

HIV Medicine 2026

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Authors: Liting Yan, Qing Xiao, Lin Tuo, Ying Liu, Naijuan Yao, Kaiju Xu, Xuemei Chen, Shuqiang Wang, Xingxiang Yang, F. Zhang
DOI: 10.1111/hiv.70192
Cited by: 0
References: 30

Abstract

Abstract Objectives This study aimed to characterize long‐term immune reconstitution trajectories and influencing factors in people living with HIV exhibiting suboptimal early immune responses after 24 months of antiretroviral therapy (ART). Methods We conducted a retrospective multicentre study from January 2016 to October 2024. Eligible participants achieved sustained virological suppression within six months of ART but maintained CD4 + T cell counts

Fields of Study & Subjects

HIV Research and Treatment HIV/AIDS Research and Interventions HIV-related health complications and treatments

Publication details

Journal / source
HIV Medicine
Volume
27
Issue
4
Pages
607–615
Publication date
5 January 2026
Language
EN