Highlights of 2025: the B‐side of LEF1

Immunology and Cell Biology 2026

View at publisher
Authors: Isabella Naylor, Adrian Y S Lee, Joanne Reed, Qian Shen
DOI: 10.1111/imcb.70129
Cited by: 1
References: 10

Abstract

In this article of the Highlights of 2025 series, we review the latest discovery of LEF1 function in B cell biology. These discoveries provide novel insights into the LEF1 function on B cell maintenance in cancer and autoimmunity, uncovering new opportunities for the development of a more specific B cell targeting approach.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers T-cell and B-cell Immunology CAR-T cell therapy research

Publication details

Journal / source
Immunology and Cell Biology
Publisher
Wiley
Volume
104
Issue
6
Pages
582–585
Publication date
3 May 2026
Language
EN