Emerging Roles for Metabolism in Myocardial Inflammation During Heart Failure
Abstract
Metabolic alterations are a hallmark of heart failure and differ across stages. The immune system plays a critical role in cardiac repair and injury during heart failure progression. Metabolic interactions between immune cells and cardiomyocytes are critical for influencing cellular states and cell-cell communications. Understanding these molecular intersections is essential to developing targeted therapies that regulate immunometabolism in the heart. In this review, we provide a comprehensive overview of the metabolic links between immune cells and cardiomyocytes during heart failure and discuss potential treatment strategies.
Fields of Study & Subjects
Cardiac Fibrosis and Remodeling
Atherosclerosis and Cardiovascular Diseases
Viral Infections and Immunology Research
Publication details
- Journal / source
- Immunological Reviews
- Publisher
- Wiley
- Volume
- 340
- Issue
- 1
- Pages
- e70128–e70128
- Publication date
- 1 July 2026
- Language
- EN