Improved prognosis prediction of all‐cause mortality and cardiovascular events by combined assessment of both ankle‐brachial index and brachial‐ankle pulse wave velocity in individuals with diabetes: The Kyushu prevention study for atherosclerosis, a prospective, multicenter survey
Abstract
AIMS/INTRODUCTION: People with diabetes exhibit early-stage cardiovascular disease (CVD). In this study, we developed a new diagnostic algorithm to predict all-cause mortality and CVD using both the ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in individuals with diabetes. MATERIALS AND METHODS: This study utilized data from the Kyushu Prevention Study for Atherosclerosis, a prospective, multicenter survey. A total of 3,933 participants with diabetes were followed. The primary outcomes were all-cause mortality and CVD. Risk was categorized based on ABI and baPWV, and the prognostic differences were evaluated. Additionally, the independence of this classification from the Framingham Risk Score (FRS) was tested. RESULTS: ABI was the strongest predictor of all-cause mortality. Individuals with a low ABI (
Fields of Study & Subjects
Peripheral Artery Disease Management
Cardiovascular Health and Disease Prevention
Diagnosis and Treatment of Venous Diseases
Publication details
- Journal / source
- Journal of Diabetes Investigation
- Publisher
- Wiley
- Volume
- 17
- Issue
- 7
- Pages
- 1172–1182
- Publication date
- 7 May 2026
- Language
- EN