Expert Consensus on the Clinical Application of Artificial Iris

OBJECTIVE: To establish evidence-based guidance to standardize the clinical application of artificial iris implantation in patients with iris defects. METHODS: A systematic literature search was performed following evidence-based consensus development standards. Eighteen international experts participated in a Delphi process to define six core clinical issues. Evidence was screened, extracted, evaluated and integrated. Recommendations were formulated through iterative expert review. RESULTS: We established six key clinical issues related to artificial iris implantation and evidence-based recommendations to address critical gaps in clinical practice. Key outcomes included standardized criteria for indications, contraindications, and type of artificial iris selection, key aspects of surgeon-patient communication, surgical management principles and critical techniques, comprehensive perioperative care protocols, and strategies for managing long-term postoperative complications associated with artificial iris implantation. CONCLUSIONS: This consensus standardizes artificial iris implantation through six evidence-based recommendations. It provides a standardized protocol for safe clinical implementation to restore visual function and cosmetic integrity in patients with iris defect.