Optimizations of Cas12a‐ and Cas12i‐based adenine base editors for efficient precision editing in the plant genome

Journal of Integrative Plant Biology 2026 Open access

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Authors: Xiaoshuang Liu, S. Jin, Zhi Xiao, Chong Ma, Qing Wang, Huanhuan Wang, Ruohan Zhou, Dongfang Gu, Rongfang Xu, Ruiying Qin, Juan Li, Pengcheng Wei
DOI: 10.1111/jipb.70177
Cited by: 2
References: 10

Abstract

A strategy coupling high-activity nucleases with dimeric TadA-8e optimizes plant Cas12-based adenine base editors, boosts editing efficiency, and provides precise editors for crop breeding and genomics research.

Fields of Study & Subjects

CRISPR and Genetic Engineering Plant Virus Research Studies RNA and protein synthesis mechanisms

Publication details

Journal / source
Journal of Integrative Plant Biology
Publisher
Wiley
Volume
68
Issue
9
Pages
3169–3171
Publication date
9 February 2026
Language
EN