Engineering the efficient Exo‐Cas12i2 for MITE manipulation in rice

Journal of Integrative Plant Biology 2026 Open access

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Authors: Nan Chai, Wuge Liu, Kangli Sun, Qian Qian, Yao‐Guang Liu, Xianrong Xie, Qinlong Zhu, Jiantao Tan
DOI: 10.1111/jipb.70254
Cited by: 1
References: 10

Abstract

Exo-Cas12i2 v1, a fusion of the 5' exonucleases T5E and PapE, facilitates editing of TA-rich regions and mediates deletions of large genomic fragments. Exo-Cas12i2 v1-driven MITE manipulation enables precise regulation of genes involved in gibberellin-mediated cell elongation and root ethylene responses to generate favorable agronomic traits.

Fields of Study & Subjects

Microfluidic and Capillary Electrophoresis Applications Plant nutrient uptake and metabolism Plant Reproductive Biology

Publication details

Journal / source
Journal of Integrative Plant Biology
Publisher
Wiley
Volume
68
Issue
9
Pages
3175–3177
Publication date
2 April 2026
Language
EN