Double dissociation between conduction aphasia and conduction agraphia supports a ventro‐dorsal partition of the left arcuate fasciculus

Journal of Neuropsychology 2026 Open access

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Authors: Valéry Mandonnet, Isabelle Poisson, Francine Chassoux, Bertrand C. Devaux, Sebastien C. Froelich, Emmanuel Mandonnet
DOI: 10.1111/jnp.70032
Cited by: 0
References: 9

Abstract

We identified in two awake surgery cases a postoperative double dissociation between phonological and graphemic output buffer deficits. Using lesion-symptom mapping from ischaemic mini-strokes and preoperative tractography, we demonstrated that the phonological (resp. graphemic) disorder fitted with ventral (resp. dorsal) damage to the AF. Further studies are needed to confirm our hypothesis of a ventro-dorsal functional organization within the AF for phonological versus graphemic processing.

Fields of Study & Subjects

Neurobiology of Language and Bilingualism Reading and Literacy Development Hemispheric Asymmetry in Neuroscience

Publication details

Journal / source
Journal of Neuropsychology
Volume
20
Issue
2
Pages
502–509
Publication date
5 February 2026
Language
EN