Improvement of Overall Skin Condition in Acne and Oily Prone Skin With an Amino Acid Cleanser Containing Salicylic Acid, Glucuronolactone, and Ceramides

BACKGROUND: Cleansers and moisturizers are two of the most essential skincare categories, both of which have significant dermatological implications. However, most studies focus on the cleansing power of surfactants and their potential damage to the skin barrier. Few studies explore the combined effects of surfactants and active ingredients on skin condition. OBJECTIVE: The main focus of this research was to explore the comprehensive improvement effects of a cleanser containing salicylic acid, glucuronolactone, and ceramides on acne and oily-prone skin. METHODS: A total of 42 volunteers used amino acid cleanser containing salicylic acid, glucuronolactone, and ceramides for 28 days. Noninvasive methods combined with dermatologist evaluation to detect skin barrier changes in TEWL, hydration, facial sebum content, acne counts, facial redness, and texture were used. Adverse reactions were also assessed. RESULTS: The results indicate that after continuous use for 4 weeks, there was a significant improvement in skin barrier function, redness, moisture content, and skin texture, while acne-related indicators also showed a significant reduction. No adverse events occurred during the entire testing process. CONCLUSION: In summary, an amino acid cleanser containing salicylic acid, glucuronolactone, and ceramides has anti-acne, repairing, soothing, and texture-improving properties, offering multidimensional improvement for acne and oily-prone skin conditions.