Prevalence and risk factors for metabolic dysfunction–associated steatotic liver disease in Sweden: Insights from the SCAPIS cohort

Journal of Internal Medicine 2026 Open access

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Authors: Oumarou Nabi, Jonas Spaak, G Bergstrom, Gunnar Engström, C J Ostgren, Andreï Malinovschi, Joel Kullberg, Anders Blomberg, Tomas Jernberg, Daniel P. Andersson, H Hagstrom
DOI: 10.1111/joim.70071
Cited by: 6
References: 56

Abstract

BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally, but its prevalence and severity remain poorly characterized in the general population. Our aim was to estimate the prevalence of MASLD and the risk of advanced fibrosis in a large Swedish general population cohort. METHODS: From the Swedish CArdioPulmonary bioImage Study (SCAPIS) cohort, we analyzed 27,763 participants aged 50-64 years who underwent extensive clinical characterization. MASLD was defined as

Fields of Study & Subjects

Liver Disease Diagnosis and Treatment Liver Disease and Transplantation Liver Diseases and Immunity

Publication details

Journal / source
Journal of Internal Medicine
Publisher
Wiley
Volume
299
Issue
4
Pages
481–501
Publication date
5 February 2026
Language
EN