Hyperpigmentation in an Infant due to Vitamin B12 Deficiency: Case Report

Journal of Paediatrics and Child Health 2026

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Authors: Edward Vertiz Barrantes, Luis Zavaleta Medina, Miriam Arredondo‐Nontol, Carmen Malca Gomez
DOI: 10.1111/jpc.70294
Cited by: 1
References: 8

Abstract

Learning Points Vitamin B12 deficiency in infants may present with neurologic and rare cutaneous signs such as distal hyperpigmentation. Maternal vegetarian or vegan diets during pregnancy and lactation increase the risk of infantile B12 deficiency. Early recognition and treatment with intramuscular hydroxocobalamin can prevent irreversible neurodevelopmental sequelae.

Fields of Study & Subjects

Folate and B Vitamins Research Porphyrin Metabolism and Disorders Infectious Encephalopathies and Encephalitis

Publication details

Journal / source
Journal of Paediatrics and Child Health
Publisher
Wiley
Volume
62
Issue
3
Pages
484–487
Publication date
21 January 2026
Language
EN