EXPRESSION OF CONCERN: Melatonin Potentiates the Antiproliferative and Pro‐Apoptotic Effects of Ursolic Acid in Colon Cancer Cells by Modulating Multiple Signaling Pathways

EXPRESSION OF CONCERN: J. Wang, W. Guo, W. Chen, W. Yu, Y. Tian, L. Fu, D. Shi, B. Tong, X. Xiao, W. Huang, and W. Deng, “Melatonin Potentiates the Antiproliferative and Pro-Apoptotic Effects of Ursolic Acid in Colon Cancer Cells by Modulating Multiple Signaling Pathways,” Journal of Pineal Research 54, no. 4 (2013): 406-416, https://doi.org/10.1111/jpi.12035. This Expression of Concern is for the above article, published online on 08 December 2012 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A third party raised concerns that the GAPDH bands in Figures 4A and 4C had been partially duplicated, cropped, and stretched. The publisher confirmed that the bands reported as GAPDH in both figure sections had derived from the same 4 bands. The authors responded to an inquiry by the publisher and reported that the data presented in Figure 4C were correct and supplied new data to replace the GAPDH band in Figure 4A. However, the authors were not able to supply an adequate explanation for how the original error occurred and were not able to supply all original data for the experiments reported in the article. Therefore, the experimental results related to these concerns cannot be verified. This Expression of Concern has been published in order to inform and alert readers about the concerns for Figures 4A and 4C. The authors were informed of this Expression of Concern.