Navigating Melatonin Safety: Fact, Fiction, and Confounders
Abstract
As a chronobiotic with sleep-promoting properties, melatonin is frequently recommended by sleep medicine practitioners and widely available as an over-the-counter drug. Recently, two publications questioned melatonin safety profile in insomnia patients, with one of these receiving vast media coverage and noticeable resonance among the general public. This letter to the Editor critically evaluates such research, offering a broader contextualization within the existing body of literature about melatonin safety and insomnia-related health outcomes.
Fields of Study & Subjects
Circadian rhythm and melatonin
Sleep and related disorders
Sleep and Wakefulness Research
Publication details
- Journal / source
- Journal of Pineal Research
- Publisher
- Wiley
- Volume
- 78
- Issue
- 2
- Pages
- e70129–e70129
- Publication date
- 1 March 2026
- Language
- EN