Experience of Cancer‐Related Fatigue in Patients With Head and Neck Cancer: A Qualitative Meta‐Synthesis

This study aimed to synthesize qualitative evidence on the lived experiences of cancer-related fatigue (CRF) in patients with head and neck cancer to inform targeted nursing interventions. Four Chinese and six English databases were systematically searched from inception to March 2025 for qualitative studies exploring CRF experiences. The quality of included studies was assessed using the JBI Critical Appraisal Checklist, and findings were synthesized using the JBI meta-aggregation methodology. Eight studies were included, generating 54 findings which were aggregated into six categories and three synthesized themes: essential characteristics and dynamic evolution; multidimensional influence and vicious circle; and management dilemmas and long-term challenges. The review highlights that CRF is a dynamic, individualized experience significantly impacting quality of life, yet current management strategies remain often insufficient. Consequently, multidisciplinary nursing interventions prioritizing comprehensive assessment, self-management support, and psychological care are essential to optimize patients' long-term adaptation and well-being.