How to Use a Variable Loop Circular Catheter to Perform Zero Fluoro Pulmonary Vein Isolation With Pulsed Field Ablation
Abstract
BACKGROUND: The variable loop circular catheter (VLCC) called VARIPULSE is a novel device designed for catheter ablation of atrial fibrillation (AFib) and electro-anatomical mapping via 3D intracardiac echocardiography (ICE). Described herein is a streamlined workflow for AFib ablation and reported feasibility, procedural efficiency, and early safety signals of the first 34 consecutive patients. The technical details of step-by-step techniques are described to serve as a practical guide for clinicians and investigators. METHODS: A retrospective, single-center review of procedural parameters was done on 34 paroxysmal and/or persistent AFib patients who were treated with a VLCC for both mapping and ablating between January 1, 2025 and May 15, 2025. The workflow of all procedures was comprised of general anesthesia administration, placement of 2 sheaths via ultrasound guided access, administration of a heparin bolus, 3D anatomical mapping of the pulmonary veins with CARTOSOUND FAM, a transeptal puncture, VLCC ablation, and then closure. Figures illustrating key procedural steps, including catheter maneuvering, are included. RESULTS: All 34 cases were done without fluoroscopy, with a median procedural time of 40.5 [IQR 19] min. After 10 procedures per operator, consistently shorter procedure times (
Fields of Study & Subjects
Atrial Fibrillation Management and Outcomes
Cardiac Arrhythmias and Treatments
Central Venous Catheters and Hemodialysis
Publication details
- Journal / source
- Pacing and Clinical Electrophysiology
- Publisher
- Wiley
- Volume
- 49
- Issue
- 8
- Pages
- 1047–1057
- Publication date
- 8 April 2026
- Language
- EN