Late‐Onset Bilateral Malignant Ciliary Body Medulloepithelioma in an Adult

Pathology International 2026 Open access

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Authors: Yuto Kaimi, Shigenobu Suzuki, Toshihide Ueno, Yukiko Nakamura, Hideki Tsuji, Hiroyuki Mano, Yasushi Yatabe, Taisuke Mori
DOI: 10.1111/pin.70086
Cited by: 1
References: 5

Abstract

We report the first case of bilateral malignant ciliary body medulloepithelioma (CBME) in an adult, with comprehensive histopathological and genomic analyses. The right eye harbored a malignant teratoid CBME with sarcomatous elements, while the left eye showed a non-teratoid variant. Whole-exome sequencing revealed shared chromosomal losses and additional aberrations in the teratoid tumor. No pathogenic germline mutations were identified. These findings suggest a potential correlation between histological subtype and genomic complexity in CBME.

Fields of Study & Subjects

Ocular Oncology and Treatments Glioma Diagnosis and Treatment Glaucoma and retinal disorders

Publication details

Journal / source
Pathology International
Publisher
Wiley
Volume
76
Issue
1
Pages
e70086–e70086
Publication date
1 January 2026
Language
EN