A quasi‐experimental study evaluating the efficacy of crossmatch‐matched platelet transfusions in hemato‐oncology patients with suspected alloimmune platelet refractoriness: A single‐centre experience

Transfusion Medicine 2026 Open access

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Authors: Daljit Kaur, Gita Negi, Vaidehi Prasanth, Joyisa Deb, Dixa Kumari, Gaurav Dhingra, Uttam Kumar Nath, Ashish Jain
DOI: 10.1111/tme.70058
Cited by: 2
References: 14

Abstract

BACKGROUND: Platelet transfusion is essential in managing thrombocytopenia in hemato-oncology patients. This study aimed to determine the prevalence of platelet refractoriness (PR) and to evaluate the efficacy of crossmatch-compatible single-donor platelet (SDP) transfusions in patients with suspected platelet refractoriness. MATERIALS AND METHODS: A two-year quasi-experimental study comprised adult and paediatric hemato-oncology patients with two consecutive low corrected count increment (CCI) responses (

Fields of Study & Subjects

Blood transfusion and management Platelet Disorders and Treatments Blood groups and transfusion

Publication details

Journal / source
Transfusion Medicine
Publisher
Wiley
Volume
36
Issue
4
Pages
377–385
Publication date
22 January 2026
Language
EN