Single-cell mechanical spectroscopy and microscopy using optical microcavities
Abstract
Natural vibrations of mesoscopic particles – including most biological cells – have remained hidden from existing technologies. Here we demonstrated the real-time measurement of natural vibrations of single mesoscopic particles using an optical microresonator, extending the reach of vibrational spectroscopy to the megahertz-gigahertz frequency window. This technology is further applied for the biomechanical fingerprinting of the species and living states of microorganisms at the single-cell level.
Fields of Study & Subjects
Mechanical and Optical Resonators
Spectroscopy Techniques in Biomedical and Chemical Research
Microfluidic and Bio-sensing Technologies
Publication details
- Journal / source
- Optical Elastography and Tissue Biomechanics
- Pages
- 34–34
- Publication date
- 4 March 2026
- Language
- EN