Fluorescence lifetime measurement based on quantum sensing

Quantum Effects and Measurement Techniques in Biology and Biophotonics 2026

View at publisher
Authors: Giuseppe Di Blasio, Federico Simoni, Lorenzo Uboldi, Ilaria Bargigia, Daniele Faccio, Giulio Cerullo, Antonio Pifferi, Cosimo D’Andrea
DOI: 10.1117/12.3080946
Cited by: 0

Abstract

Quantum light sources, such as entangled photons, offers unique advantages for bio-sensing of light sensitive samples, providing background free and high SNR measurements at ultra-low photon flux. We built a modular set-up based on SPDC entangled photon pairs generation by using a pulsed laser and several single-photon detectors with different time resolution and quantum efficiency to investigate fluorescent complexes. This toolkit paves the way for minimally invasive fluorescence lifetime sensing towards next generation in vivo studies.

Fields of Study & Subjects

Advanced Fluorescence Microscopy Techniques Quantum Information and Cryptography Quantum optics and atomic interactions

Publication details

Journal / source
Quantum Effects and Measurement Techniques in Biology and Biophotonics
Pages
28–28
Publication date
4 March 2026
Language
EN