Mechanism of giant magnetic field effect in a red fluorescent protein

Quantum Effects and Measurement Techniques in Biology and Biophotonics 2026

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Authors: Adam E. Cohen
DOI: 10.1117/12.3082284
Cited by: 0

Abstract

We found that mScarlet3 fluorescence in E. coli reversibly decreased by 21% in the presence of a 60 mT magnetic field, the largest magnetic field effect (MFE) reported in any fluorescent protein. We developed a quantitative model of the giant MFE in mScarlet3. Our quantitative model of the photocycle provides a framework for the design and optimization of magnetic-field-sensitive proteins, opening possibilities in fluorescent protein-based magnetometry, magnetic imaging, and magnetogenetic control.

Fields of Study & Subjects

Advanced Fluorescence Microscopy Techniques Electromagnetic Fields and Biological Effects Photoreceptor and optogenetics research

Publication details

Journal / source
Quantum Effects and Measurement Techniques in Biology and Biophotonics
Pages
31–31
Publication date
4 March 2026
Language
EN