Adaptive optics-free in vivo measurements of individual cones’ responses to light stimulation

We present results from in vivo measurements of single cones’ responses to light stimulation without the use of hardware adaptive optics. In our approach the cone images are obtained through the numerical aberrations correction which is done after data acquisition. From such corrected data we extract the single cones’ optoretinograms. Both baseline before the stimulation and the response of each detected cone can be clearly distinguished in the obtained results. Additionally, the responses can be classified into two groups corresponding to M and L cones.