Structural variation tunes apoptotic responses to drive immune escape in melanoma
Abstract
Copy-number variation reshapes apoptotic gene dosage to drive acquired immunotherapy resistance in melanoma.
Fields of Study & Subjects
Phagocytosis and Immune Regulation
Cancer Immunotherapy and Biomarkers
Cell death mechanisms and regulation
Publication details
- Journal / source
- Science Immunology
- Publisher
- American Association for the Advancement of Science (AAAS)
- Volume
- 11
- Issue
- 115
- Pages
- eaef3843–eaef3843
- Publication date
- 16 January 2026
- Language
- EN