IgG4 on the dance floor: Partners swapped by Fab-arm exchange

Science Immunology 2026

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Authors: Ailis Grieshaber, Kevin C. O’Connor

DOI: 10.1126/sciimmunol.aeg6827

Cited by: 0

References: 1

Abstract

Proteomic analysis shows that nearly all circulating human IgG4 undergoes Fab-arm exchange, creating a vast bispecific antibody repertoire.

Monoclonal and Polyclonal Antibodies Research IgG4-Related and Inflammatory Diseases T-cell and B-cell Immunology

References 1