The rise of spatial TCR profiling: Emerging technologies and open challenges

Science Immunology 2026

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Authors: Yinglu Tang, Tao Wang
DOI: 10.1126/sciimmunol.aeg7517
Cited by: 1
References: 12

Abstract

High-definition spatial TCR profiling illuminates how clonal identity and T cell state are coordinated in the tumor microenvironment (see related Research Article by McCord et al. ).

Fields of Study & Subjects

Single-cell and spatial transcriptomics CAR-T cell therapy research Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Science Immunology
Publisher
American Association for the Advancement of Science (AAAS)
Volume
11
Issue
118
Pages
eaeg7517–eaeg7517
Publication date
10 April 2026
Language
EN