The elephant in the adhesion GPCR room
Abstract
Adhesion GPCRs are a family of surface receptors involved in many developmental and physiological decisions in every organ system. In this issue of Science Signaling , Bernadyn et al. report insights into the activation mechanism and cellular functions of the adhesion GPCR GPR97/ADGRG3.
Fields of Study & Subjects
Receptor Mechanisms and Signaling
Protein Kinase Regulation and GTPase Signaling
Ion Channels and Receptors
Publication details
- Journal / source
- Science Signaling
- Volume
- 19
- Issue
- 925
- Pages
- eaed6070–eaed6070
- Publication date
- 17 February 2026
- Language
- EN