SIRT2 versus Lck

Science Signaling 2026

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Authors: John F. Foley
DOI: 10.1126/scisignal.aeg1336
Cited by: 0
References: 1

Abstract

Inhibiting the deacetylase SIRT2 increases the activity of the kinase Lck to enhance T cell receptor signaling.

Fields of Study & Subjects

Sirtuins and Resveratrol in Medicine T-cell and B-cell Immunology Histone Deacetylase Inhibitors Research

Publication details

Journal / source
Science Signaling
Volume
19
Issue
924
Pages
eaeg1336–eaeg1336
Publication date
10 February 2026
Language
EN