Salmonella Stanley ST29 carrying IncHI2/ST3- bla NDM-5 plasmid emerged in a 4-month-old infant with diarrhea

Antimicrobial Agents and Chemotherapy 2026 Open access

Read full text
Authors: Yuman Bai, Xiaojuan Gao, Chao Yue, Zhongpeng Cai, Ming-Yi Gao, Luchao Lv, Yi-hua Cai, Hongmei Mo, Jian–Hua Liu
DOI: 10.1128/aac.01471-25
Cited by: 1
References: 13

Abstract

ABSTRACT Salmonella serovar Stanley ST29 is an emerging foodborne pathogen with community spread potential, while its carbapenem resistance remains uncommon. In a longitudinal pediatric case with diarrhea, two clonal ST29 isolates sampled 2 months apart revealed within-host evolutionary dynamics: Tn 7051 -mediated excision of bla NDM-5 from an IncHI2/ST3 plasmid. Moreover, phylogenomics connected the case isolate to strains from a healthy carrier and from food-chain-associated sources in the same region (17–18 SNPs), underscoring community dissemination and the need for One-Health surveillance.

Fields of Study & Subjects

Salmonella and Campylobacter epidemiology Escherichia coli research studies Antibiotic Resistance in Bacteria

Publication details

Journal / source
Antimicrobial Agents and Chemotherapy
Publisher
American Society for Microbiology
Volume
70
Issue
3
Pages
e0147125–e0147125
Publication date
4 February 2026
Language
EN