Ocular manifestations in a cohort of patients with mpox in the Democratic Republic of the Congo 2007–2011

ASM Case Reports 2026 Open access

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Authors: Placide Mbala-Kingebeni, Nam V. Nguyen, Jean-Claude Mwanza, Jessica H. Carag, Susanne L. Linderman, Tolulope Fashina, Eddy Kinganda, Tony Wawina-Bokalanga, Amuri Aziza, Jean-Claude Makangara-Cigolo, Emmanuel Hasivirwe Vakaniaki, Yvon Anta
+15 more Jepsy Yango, Olivier Tshiani, Jason Kindrachuk, Laurens Liesenborghs, Christophe Van Dijck, Martine Peeters, Éric Delaporte, Anne W. Rimoin, John W. Huggins, Therese Riu-Rovira, Steve Mundeke Ahuka, James W. Martin, Ian Crozier, Steven Yeh, JJ Muyembe
DOI: 10.1128/asmcr.00171-25
Cited by: 1
References: 12

Abstract

This report describes the ocular manifestations in a cohort of patients with Clade I mpox evaluated in the Democratic Republic of the Congo from 2007 to 2011, as well as the clinical course of a 3-year-old patient with mpox associated with ocular disease. Among 216 patients, ocular manifestations were observed in 8.3%, including conjunctivitis, eyelid lesions, eyelid swelling, eye pain, orbital swelling, keratitis, and corneal staphyloma. These findings highlight the broad spectrum of ocular manifestations with potentially sight-threatening consequences in patients with mpox.

Fields of Study & Subjects

Poxvirus research and outbreaks Autoimmune Neurological Disorders and Treatments Virology and Viral Diseases

Publication details

Journal / source
ASM Case Reports
Publisher
American Society for Microbiology
Volume
2
Issue
2
Publication date
11 February 2026
Language
EN