Fungal diagnostic stewardship in immunocompromised populations: a focus on molds and dimorphic fungi

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Authors: Julie M. Steinbrink, Daniel Friedman, George R. Thompson, Carol A. Kauffman, Barbara D. Alexander, Kimberly E. Hanson, Hannah Imlay
Cited by: 2
References: 140

Abstract

SUMMARYInvasive fungal diseases cause severe illness and death in immunocompromised patients. Antifungal use is increasingly common, as is fungal diagnostic testing. However, these efforts have not been guided by traditional stewardship efforts akin to those used for bacterial infections. Fungal diagnostic stewardship can have a significant impact on the care of vulnerable patients, including decreasing unnecessary testing while increasing appropriate testing and improving testing strategies to reduce diagnostic errors. In this review, we discuss the most frequently used fungal diagnostic assays for molds and dimorphic fungal infections, their diagnostic performance for these organisms in immunocompromised hosts, and strategies to improve diagnostic stewardship and ultimately patient outcomes.

Fields of Study & Subjects

Antifungal resistance and susceptibility Fungal Infections and Studies Ocular Infections and Treatments

Publication details

Journal / source
Clinical Microbiology Reviews
Publisher
American Society for Microbiology
Volume
39
Issue
1
Pages
e0024225–e0024225
Publication date
12 February 2026
Language
EN