Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research
Abstract
Organoids have revolutionized human biomedical research since their development in 2010. However, as nearly 75% of human infectious diseases originate in animals, animal-derived organoids are essential to complement human models, yet their development in veterinary contexts remains scarce. Organoids replicate native tissue architecture, enabling species-specific and comparative studies of viral infection and host response. Thus, animal organoids represent a powerful field in organoid technology, advancing cross-species virology research and strengthening strategies for zoonotic disease preparedness.
Fields of Study & Subjects
Zoonotic diseases and public health
Animal testing and alternatives
Poxvirus research and outbreaks
Publication details
- Journal / source
- Journal of Virology
- Publisher
- American Society for Microbiology
- Volume
- 100
- Issue
- 3
- Pages
- e0219725–e0219725
- Publication date
- 3 March 2026
- Language
- EN