Lon protease-mediated secretome profiling in Klebsiella pneumoniae
Abstract
ABSTRACT Lon protease is a global regulator in bacteria affecting biofilm formation, antibiotic resistance, toxin-antitoxin complexes, and proteolysis of damaged proteins. In Klebsiella pneumoniae , Lon has roles in iron response, protein transport, and membrane assembly. Here, we apply bottom-up proteomics to identify proteins in the extracellular environment of WT and Δ lon K. pneumoniae .
Fields of Study & Subjects
Bacterial Genetics and Biotechnology
Advanced Proteomics Techniques and Applications
Heat shock proteins research
Publication details
- Journal / source
- Microbiology Resource Announcements
- Volume
- 15
- Issue
- 4
- Pages
- e0031125–e0031125
- Publication date
- 4 March 2026
- Language
- EN