Synthesis of Dicarbazoles and Carbazole-(2,3,4,9-tetrahydro-1H-carbazoles) Linked by Polyether Spacers
Abstract
Abstract An effective approach was developed to the synthesis of dicarbazoles and carbazole–tetrahydrocarbazole hybrids tethered via di- or triethylene glycol spacers. These polyether spacers are susceptible to metabolic cleavage, enabling targeted delivery of the bioactive moiety to functionally important enzyme active sites.
Fields of Study & Subjects
Heterocyclic Compound Synthesis and Bioactivity
Chemical Synthesis and Analysis
Click Chemistry and Applications
Publication details
- Journal / source
- Russian Journal of General Chemistry
- Volume
- 96
- Issue
- 4
- Publication date
- 26 February 2026
- Language
- EN