Novel Nitrosyl Complexes of Tetrahedral Iron with 5-Substituted 1,3,4-Oxadiazole-2-thiols

Russian Journal of General Chemistry 2026

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Authors: Evgeniya A. Syreyshchikova, S. Ya. Gadomsky, Maxim A. Blagov, А. В. Куликов, Olesya Viktorovna Pokidova, Н. А. Санина, Sergey M. Aldoshin
DOI: 10.1134/s1070363225606829
Cited by: 0
References: 28

Abstract

Abstract Nitrosyl complexes of tetrahedral iron—nitric oxide (NO) donors—with 5-substituted 1,3,4-oxadiazole-2-thiols were obtained for the first time. According to elemental analysis data, spectral methods, and quantum chemical calculations, there are paramagnetic tetrairon nitrosyl complexes of the μ-NCS structural type. The NO-donor properties and the effect of the obtained compounds on phosphodiesterase (PDE) activity were studied. It was shown that the synthesized complexes exhibit effective PDE inhibitory activity.

Fields of Study & Subjects

Inorganic and Organometallic Chemistry Structural and Chemical Analysis of Organic and Inorganic Compounds Crystal structures of chemical compounds

Publication details

Journal / source
Russian Journal of General Chemistry
Volume
96
Issue
4
Publication date
3 March 2026
Language
EN