New Nicotinonitrile–Coumarin Heterodimers: Synthesis and Evaluation of Agrochemical Potential

Russian Journal of General Chemistry 2026

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Authors: Tagir L. Salakhov, Victor V. Dotsenko, Daria Yu. Lukina, Vladimir D. Strelkov, Sergey Gennadievich Krivokolysko, Evgeniy E. Netreba, Elena P. Dotsenko, Nicolai A. Aksenov, Inna V. Aksenova
DOI: 10.1134/s1070363225608488
Cited by: 1
References: 74

Abstract

Abstract Previously undescribed nicotinonitrile–coumarin hybrids, namely 2-{[2-oxo-2-(2-oxo-2H-chromen-3-yl)ethyl]thio}pyridine-3-carbonitriles and -quinoline-3-carbonitriles, were synthesized via the reaction of 2-thioxo-1,2-dihydropyridine-3-carbonitriles with 3-(bromoacetyl)coumarin or 3-(bromoacetyl)benzo[f]coumarin in the presence of sodium propylate. Under laboratory conditions on sunflower seedlings, some of the prepared compounds exhibited a pronounced antidote effect against the herbicide 2,4-D, as well as moderate growth-stimulating activity.

Fields of Study & Subjects

Synthesis and biological activity Synthesis of Organic Compounds Synthesis and Reactivity of Sulfur-Containing Compounds

Publication details

Journal / source
Russian Journal of General Chemistry
Publisher
Pleiades Publishing Ltd
Volume
96
Issue
2
Publication date
1 February 2026
Language
EN