Synthesis of Bis(hydroxymethyl) 1,4-Disubstituted 1,2,3-Triazoles Derivatives
Abstract
Abstract The article deals with the synthesis of new diacetoxymethyl and dichloromethyl derivatives of 1,4-disubstituted 1,2,3-triazoles by the reaction of acetylation with acetic anhydride and chlorination with thionyl chloride of the starting 2-nitro-1,3-bis(4,4'-dihydroxymethyl)-1,2,3-triazolyl-2-azapropane and 3-nitro-1,5-bis(4,4'-dihydroxymethyl)-1,2,3-triazolyl-3-azapentane. The structure of the obtained compounds is confirmed by IR and NMR spectroscopy. These compounds are of interest as starting materials for the synthesis of new biologically active and high-energy substances.
Fields of Study & Subjects
Click Chemistry and Applications
Synthesis and Reactivity of Heterocycles
Synthesis and Characterization of Heterocyclic Compounds
Publication details
- Journal / source
- Russian Journal of Applied Chemistry
- Publisher
- Pleiades Publishing Ltd
- Volume
- 99
- Issue
- 1
- Pages
- 22–26
- Publication date
- 1 January 2026
- Language
- EN