Delayed neurological events after mumps vaccination: implications for surveillance and clinical recognition

BMJ Case Reports 2026

View at publisher
Authors: Masazumi Miyahara, Kyoko Osaki, Manami Negoro, Shigeru Suga
DOI: 10.1136/bcr-2025-271248
Cited by: 1
References: 6

Abstract

We report a case of febrile status epilepticus with aseptic meningitis occurring 23 days after mumps vaccination (Hoshino strain) in a previously healthy male infant. The vaccine strain was identified in cerebrospinal fluid by reverse transcription-PCR and sequencing. This case may illustrate potential blind spots in current vaccine safety surveillance, which often rely on short monitoring windows and passive reporting. It suggests that consideration of longer surveillance periods, improved clinician awareness of delayed neurological complications and greater diagnostic vigilance may be warranted. The patient recovered fully without sequelae.

Fields of Study & Subjects

Virology and Viral Diseases Bacterial Infections and Vaccines Vaccine Coverage and Hesitancy

Publication details

Journal / source
BMJ Case Reports
Publisher
BMJ
Volume
19
Issue
2
Pages
e271248–e271248
Publication date
1 February 2026
Language
EN