Associations between obesity, metabolic syndrome and glaucoma in the National Institutes of Health ‘All of Us’ research programme

British Journal of Ophthalmology 2026

View at publisher
Authors: Megan Paul, Jennifer Lee, Ken Kitayama, Deyu Pan, F. Richard Yu, Victoria L. Tseng, Anne L. Coleman
DOI: 10.1136/bjo-2025-328112
Cited by: 3
References: 53

Abstract

BACKGROUND/AIMS: The literature surrounding the relationship between obesity and glaucoma is conflicting. The aim of this study was to examine associations between obesity, metabolic syndrome (MetS) and glaucoma prevalence in the National Institutes of Health All of Us (AoU) research programme. METHODS: 156 362 individuals over age 40 were included in analyses. Obesity was defined by (1) body mass index (BMI) and (2) central obesity based on waist circumference (WC). MetS was defined as ≥3 of the following: central obesity (CO), triglycerides ≥150 mg/dL, high-density lipoprotein cholesterol (

Fields of Study & Subjects

Glaucoma and retinal disorders Retinal Diseases and Treatments Ophthalmology and Visual Impairment Studies

Publication details

Journal / source
British Journal of Ophthalmology
Publisher
BMJ
Volume
110
Issue
9
Pages
1057–1063
Publication date
28 January 2026
Language
EN