Proactive treatment regimen with dexamethasone implant for diabetic and post-occlusive macular oedema: the ProDEX-2 study

British Journal of Ophthalmology 2026 Open access

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Authors: Pasquale Viggiano, Tunde Peto, Mariagrazia Pignataro, Alba Chiara Termite, Giacomo Boscia, Maria Oliva Grassi, Maria Giovanna Malerba, Federica Evangelista, Sara Mavaddati, Stefano Dore, Giovanni Alessio, Stela Vujosevic
+1 more Francesco Boscia
DOI: 10.1136/bjo-2025-328550
Cited by: 1
References: 34

Abstract

PURPOSE: To evaluate the efficacy of proactive treatment with intravitreal dexamethasone implant (DEX-implant) at fixed 4-month intervals in treatment-naïve patients with diabetic macular oedema (DMO) and retinal vein occlusion (RVO), stratified by baseline visual acuity. METHODS: Sixty-one treatment-naïve eyes (35 DMO, 26 RVO) received DEX-implant at 4-month intervals with possible adjustment (3.5-4.5 months) based on anatomical response. Patients were stratified by baseline visual acuity (

Fields of Study & Subjects

Retinal Diseases and Treatments Retinal and Macular Surgery Retinal Imaging and Analysis

Publication details

Journal / source
British Journal of Ophthalmology
Publisher
BMJ
Pages
bjo–2025
Publication date
5 June 2026
Language
EN