UK National Screening Committee position statement on surrogate outcomes in cancer screening trials

BMJ 2026 Open access

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Authors: Sarah Batson, Allan Hackshaw, Anne Mackie, Mike Richards, Rosalind Given-Wilson, Emma Atakpa, Edmund Njeru Njagi, Bethany Shinkins, Tom Callender, Chris Hyde, Cristina Visintin, David Thompson
+6 more Eleanor Cozens, Gareth Evans, Karla Hemming, K. Payne, Steve Halligan, Sian Taylor-Phillips
DOI: 10.1136/bmj-2026-629407
Cited by: 3
References: 20

Abstract

Surrogate outcomes may offer earlier evidence of benefit and initiate further evaluative work, but they cannot yet replace mortality as the definitive outcome in cancer screening trials, say Sian Taylor-Phillips and colleagues

Fields of Study & Subjects

Cancer Genomics and Diagnostics BRCA gene mutations in cancer Ethics in Clinical Research

Publication details

Journal / source
BMJ
Publisher
BMJ
Volume
393
Pages
e629407–e629407
Publication date
25 May 2026
Language
EN