Public preferences and decision-making for mpox vaccination in the African region: a multinational discrete choice experiment

INTRODUCTION: After the WHO prequalified the first vaccine against mpox, we aimed to identify the influence of vaccine attributes on mpox vaccination preferences among the African adults. METHODS: A discrete choice experiment was conducted among 1832 African adults across six countries. Respondents answered eight questions, each requiring them to choose between two hypothetical vaccines, with variations in distance from home to vaccination facilities, cost, effectiveness, duration of the protective effect, supply and side effects. A mixed logit model was employed to estimate vaccination preferences. Willingness to pay and changes in probability were also estimated from the regression coefficients. RESULTS: The strongest vaccine attribute was the higher effectiveness of vaccines (≥90% vs