Risk of developing pneumococcal disease in individuals under 19 years of age with chronic medical conditions: a retrospective cohort study using a Japanese insurance claims database

BMJ Open 2026 Open access

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Authors: Aya Yano, K. Imai, Youngju Kim, Masahiro Sando, Naruhiko Ishiwada
DOI: 10.1136/bmjopen-2025-105479
Cited by: 1
References: 31

Abstract

OBJECTIVES: To evaluate the risk of invasive pneumococcal disease (IPD) and non-bacteraemic pneumonia (NBP)/acute otitis media (AOM)/sinusitis in Japanese individuals under 19 years of age with chronic medical conditions (CMCs) compared with those without. DESIGN: An observational, retrospective, cohort study. SETTING: A large, longitudinal health insurance claims database in Japan (JMDC database). PARTICIPANTS: A total of 12.3 million individuals aged

Fields of Study & Subjects

Pneumonia and Respiratory Infections Respiratory viral infections research Antibiotic Use and Resistance

Publication details

Journal / source
BMJ Open
Publisher
BMJ
Volume
16
Issue
1
Pages
e105479–e105479
Publication date
1 January 2026
Language
EN