Omega-3 polyunsaturated fatty acid supplementation for muscle health in community-dwelling older adults at high risk of sarcopenia: protocol for a multicentre, randomised, double-blind, placebo-controlled trial

BMJ Open 2026 Open access

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Authors: Zechen Zhang, Yifan Jiang, Songyue Su, Linlin Wang, Dongsheng Bian
DOI: 10.1136/bmjopen-2025-113455
Cited by: 0
References: 36

Abstract

INTRODUCTION: Sarcopenia imposes a substantial burden on society, while omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation holds the potential for preventing and treating this condition. This study aims to investigate the efficacy of three different n-3 PUFA supplementation regimens compared with each other and to corn oil placebo intervention on muscle health in community-dwelling older adults at high risk of sarcopenia. METHODS AND ANALYSIS: A total of 400 community-dwelling older adults aged 60 years or older, with handgrip strength

Fields of Study & Subjects

Nutrition and Health in Aging Fatty Acid Research and Health Muscle Physiology and Disorders

Publication details

Journal / source
BMJ Open
Volume
16
Issue
2
Pages
e113455–e113455
Publication date
1 February 2026
Language
EN