25 Metabolic versus non-metabolic profiles and risk of Achilles tendinopathy: a propensity score–matched analysis of 7.5 million patients

Introduction Metabolic disorders have been increasingly linked to tendon pathology. This study evaluated whether individuals with metabolic risk factors have a greater risk of developing Achilles tendinopathy (AT) compared with metabolically healthy individuals using real-world electronic health record data.Materials and Methods A retrospective cohort analysis was performed using a global federated research network (TriNetX) with data from 151–158 healthcare organisations. Adults (≥18 years) with BMI>30kg/m 2 and ≥2 metabolic risk factors—hypertension, elevated HbA1c (≥5.7%), low HDL (