Megamitochondria in alcohol-associated liver disease and cancer: a friend or foe?

eGastroenterology 2026 Open access

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Authors: Mengwei Niu, Xiaoli Wei, Xiaowen Ma, Wen-Xing Ding
DOI: 10.1136/egastro-2026-100408
Cited by: 1
References: 5

Abstract

Dated back to the 1970s, megamitochondria (giant mitochondria) were discovered in liver biopsy specimens from patients with alcohol-associated liver disease (ALD) using light and electron microscopy.

Fields of Study & Subjects

Alcohol Consumption and Health Effects Alcoholism and Thiamine Deficiency Liver Disease Diagnosis and Treatment

Publication details

Journal / source
eGastroenterology
Publisher
BMJ
Volume
4
Issue
2
Pages
e100408–e100408
Publication date
1 April 2026
Language
EN